The Therapeutic Potential of Plant Polysaccharides in Metabolic Diseases

Wang, Xiao-Fang and Chen, Xue and Tang, Yong and Wu, Jian-Ming and Qin, Da-Lian and Yu, Lu and Yu, Chong-Lin and Zhou, Xiao-Gang and Wu, An-Guo (2022) The Therapeutic Potential of Plant Polysaccharides in Metabolic Diseases. Pharmaceuticals, 15 (11). p. 1329. ISSN 1424-8247

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Abstract

Plant polysaccharides (PPS) composed of more than 10 monosaccharides show high safety and various pharmacological activities, including immunoregulatory, antitumor, antioxidative, antiaging, and other effects. In recent years, emerging evidence has indicated that many PPS are beneficial for metabolic diseases, such as cardiovascular disease (CVD), diabetes, obesity, and neurological diseases, which are usually caused by the metabolic disorder of fat, sugar, and protein. In this review, we introduce the common characteristics and functional activity of many representative PPS, emphasize the common risks and molecular mechanism of metabolic diseases, and discuss the pharmacological activity and mechanism of action of representative PPS obtained from plants including Aloe vera, Angelica sinensis, pumpkin, Lycium barbarum, Ginseng, Schisandra chinensis, Dioscorea pposite, Poria cocos, and tea in metabolic diseases. Finally, this review will provide directions and a reference for future research and for the development of PPS into potential drugs for the treatment of metabolic diseases.

Item Type: Article
Uncontrolled Keywords: plant polysaccharides; metabolic disease; characteristics; pharmacological activities; mechanism of action
Subjects: Institute Archives > Medical Science
Depositing User: Managing Editor
Date Deposited: 08 Nov 2022 04:17
Last Modified: 22 Aug 2023 06:57
URI: http://eprint.subtopublish.com/id/eprint/69

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