Nintedanib-Mediated Improvement in CT Imaging in Pulmonary Fibrosis Associated with Systemic Scleroderma

Nishino, Kengo and Sasatani, Yuika and Ohara, Gen and Kagohashi, Katsunori and Satoh, Hiroaki (2021) Nintedanib-Mediated Improvement in CT Imaging in Pulmonary Fibrosis Associated with Systemic Scleroderma. Advances in Respiratory Medicine, 89 (5). pp. 528-531. ISSN 2543-6031

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Abstract

Nintedanib is an antifibrotic drug that has an inhibitory effect on growth factor tyrosine kinases. In patients with idiopathic pulmonary fibrosis and systemic scleroderma-associated interstitial pneumonia (SSc-IP), nintedanib has been effective in suppressing the decline in forced vital capacity over time and the onset of acute exacerbation of interstitial pneumonia. Here, we report a SSc-IP patient who showed an improvement on CT images following nintedanib treatment. To our knowledge, this is the first report of such a case. Although SSc-IP patients are very rare, additional clinical experience and understanding will be required to prove the therapeutic benefit of nintedanib in these cases in relation to improved chest images.

Item Type: Article
Subjects: Institute Archives > Medical Science
Depositing User: Managing Editor
Date Deposited: 01 Mar 2023 04:50
Last Modified: 23 May 2024 05:13
URI: http://eprint.subtopublish.com/id/eprint/465

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