Aouine, Younas and Labriti, Brahim and Alami, Anouar and Faraj, Hassane and Hallaoui, Abdelilah El (2020) Synthesis and Characterization of Racemic 2-(tert- Butoxycarbonylamino)-2-methyl-3-(1H-1,2,4-triazol- 1-yl)propanoic Acid, a New Derivative of β-(1,2,4- Triazol-1-yl)alanine. B P International. ISBN 978-93-89816-77-8
Full text not available from this repository.Abstract
A simple synthetic approach to racemic N-tert-butyloxycarbonyl-2-methyl-3-(1H-1,2,4-triazol-1-
yl)alanine 5 in four steps and 68% overall yield starting from oxazoline derivative 1 is reported. This
synthesis involves the alkylation of 1H-1,2,4-triazole with an O-tosyloxazoline derivative, followed by
an oxazoline ring-opening reaction and oxidation of the N-protected β-aminoalcohol by potassium
permanganate.
| Item Type: | Book |
|---|---|
| Subjects: | Institute Archives > Chemical Science |
| Depositing User: | Managing Editor |
| Date Deposited: | 14 Nov 2023 11:03 |
| Last Modified: | 14 Nov 2023 11:03 |
| URI: | http://eprint.subtopublish.com/id/eprint/3614 |
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