IONIC STATE AND ATPASE ACTIVITY DURING SELENITE CATARACTOGENESIS IN WISTAR RATS

MATHEW, JOE PRASAD and THOMAS, V.C. and THOMAS, ISSAC (2003) IONIC STATE AND ATPASE ACTIVITY DURING SELENITE CATARACTOGENESIS IN WISTAR RATS. UTTAR PRADESH JOURNAL OF ZOOLOGY, 23 (1). pp. 79-86.

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Abstract

Selenite cataract is an experimental model cataract which can be produced by administering Sodium selenite in microgram quantities subcutaneously in suckling rat pups. During the present study, sodium, postassium, calcium and magnesium in the lens were measured at various stages after subcutaneous selenite administration in multiple low (chronic) and single high (acute) dosages in Wistar rats. Since selenite is a potent oxidant of membrane SH-groups, the activity of the main transport enzyme ATPases were determined alongwith the ion analysis to understand the role of oxidative damage and the alteration of membrane permeability and cation transport in the rat lens during cataractogenesis.

Item Type: Article
Subjects: Institute Archives > Biological Science
Depositing User: Managing Editor
Date Deposited: 10 Nov 2023 03:38
Last Modified: 10 Nov 2023 03:38
URI: http://eprint.subtopublish.com/id/eprint/3471

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