Effect of Aging on Homeostasis in the Soft Tissue of the Periodontium: A Narrative Review

Kim, Yu Gyung and Lee, Sang Min and Bae, Sungeun and Park, Taejun and Kim, Hyeonjin and Jang, Yujeong and Moon, Keonwoo and Kim, Hyungmin and Lee, Kwangmin and Park, Joonyoung and Byun, Jin-Seok and Kim, Do-Yeon (2021) Effect of Aging on Homeostasis in the Soft Tissue of the Periodontium: A Narrative Review. Journal of Personalized Medicine, 11 (1). p. 58. ISSN 2075-4426

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Abstract

Aging is characterized by a progressive decline or loss of physiological functions, leading to increased susceptibility to disease or death. Several aging hallmarks, including genomic instability, cellular senescence, and mitochondrial dysfunction, have been suggested, which often lead to the numerous aging disorders. The periodontium, a complex structure surrounding and supporting the teeth, is composed of the gingiva, periodontal ligament, cementum, and alveolar bone. Supportive and protective roles of the periodontium are very critical to sustain life, but the periodontium undergoes morphological and physiological changes with age. In this review, we summarize the current knowledge of molecular and cellular physiological changes in the periodontium, by focusing on soft tissues including gingiva and periodontal ligament.

Item Type: Article
Subjects: Institute Archives > Medical Science
Depositing User: Managing Editor
Date Deposited: 06 Dec 2022 12:34
Last Modified: 23 Aug 2023 04:20
URI: http://eprint.subtopublish.com/id/eprint/270

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