Transpedical interbody bone grafting in the treatment of senile osteoporotic vertebral fracture

Objective: To evaluate the clinical effect of transpedical interbody bone grafting in the treatment of senile osteoporotic vertebral fracture.

Methods: Eighty-six elders with osteoporotic vertebral fracture were selected and divided into a control group and a test group using random double-blind method. Patients in the control group were treated by short-segment transpedicular screw system internal fixation, while patients in the test group were treated by short-segment transpedicular screw system internal fixation in combination with transpedical interbody bone grafting. Operation related indexes and fracture recovery condition were compared between the two groups.

Results: The overall effective rate of the test group was 93.02%, much higher than the control group (76.74%) (P<0.05). The difference of operation duration, intraoperative bleeding volume, length of hospital stay, fracture healing time, preoperative vertebral height loss and preoperative Cobb’s angle between the two groups had no statistical significance (P>0.05). The postoperative pain score of the test group was lower than that of the control group, and the difference was statistically significant (P<0.05). The vertebral height loss and Cobb’s angle of the test group were superior to those of the control group at the last follow up, and the difference had statistical significance (P<0.05). The incidence of internal fixator loosening of the test group was much lower than that of the control group (P<0.05).

Conclusion: Short-segment transpedicular screw system internal fixation in combination with transpedical interbody bone grafting shows favorable effects in the treatment senile osteoporotic vertebral fracture, resulting in mild pain and less loss of vertebral height and angle; hence it is worth promotion in clinic.