Bullous Pemphigoid- A Rare Case report

Wanjari, Mayur B. and Mendhe, Deeplata and Wankhede, Pratibha and Alwadkar, Sagar and Rodge, Hina (2021) Bullous Pemphigoid- A Rare Case report. Journal of Pharmaceutical Research International, 33 (44A). pp. 151-155. ISSN 2456-9119

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Abstract

Introduction: The most severe autoimmune subepidermal blistering condition of the skin and mucous membranes is bullous pemphigoid (BP). In Europe, it is estimated to affect 1 in every 4,000 people. Currently incidence range between 2-22/1,000,000 worldwide. It primarily affects the elderly and is diagnosed using clinical, histologic, and immunologic criteria. Clinically, it appears as diffuse eczematous, pruritic, urticaria-like lesions with the later emergence of tense bullae or blistering lesions filled with clear fluid.

Case Presentation: Here, we report a case of a 50- years old female patient with a complaint of itchy lesions with wounds all over the body present with an 8-month of history. A subepidermal blister with eosinophils and neutrophils infiltration was discovered on histopathological evaluation. Salt-split indirect immunofluorescence revealed linear deposition of IgG at the dermo-epidermal junction. On further investigation, using diagnostic and Interventional aids a final diagnosis of Bullous pemphigoid.

Item Type: Article
Subjects: Institute Archives > Medical Science
Depositing User: Managing Editor
Date Deposited: 28 Apr 2023 04:15
Last Modified: 21 Mar 2024 04:16
URI: http://eprint.subtopublish.com/id/eprint/1810

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