Prospective Study: Optic Nerve Sheath ‎Diameter in Prediction of Fluid ‎Responsiveness in Sepsis Patients

Background: Sepsis is a life-threatening disease caused by the body's reaction to infection, which results in tissue destruction, organ failure, and death. Sepsis affects at least 30 million people worldwide each year, with 6 million people dying as a result. The goal of the research was to see whether the measurement of the Optic Nerve Sheath Diameter (ONSD) could be used to predict fluid responsiveness in hemodynamically unstable individuals.‎

Patients and Methods: This prospective observational (cohort) study was conducted at Tanta ‎University Hospitals in the Surgical Intensive Care Unit for 6 months at least ‎after approval from institutional ethics committee‎.

Results: Demographic data (sex, illiteracy, height, BMI) in our patients of the study there ‎were 34 (81%) male, 8 (19%) female, the age was average from 50.33 (±8.63 ‎SD) with range (25-65), 9 (21.4%) illiterate, 10 (23.8%) primary, 18 (42.9%) ‎secondary, 5 (11.9%) university, the mean value of weight 80.29 (±9.45 SD) ‎with range (60.7-98.8), the mean value of height 170.57 (±7.24 SD) with ‎range (157-182), the mean value of BMI 27.54 (±2.19 SD) with range (24.3-‎‎32).‎

Conclusion: In patients with sepsis, ocular ultrasonography appears to be a non-invasive and simple-to-learn technique for assessing overall fluid status. It may be particularly effective in finding those septic individuals who should avoid further fluid intake since it could cause pulmonary edema or other fluid-related problems.