Nifedipine or Labetalol: Hypertension Management during Pregnancy

Hasan, Mohammad and Ahad, Syed Abdul and Ahmad, Shahzaib and Mumtaz, Hassan and Asghar, Neelam and Imtiaz, Hassan and Yusufzai, Atif and Sohail, Ahmed and Khan, Zoobia Z (2021) Nifedipine or Labetalol: Hypertension Management during Pregnancy. Journal of Advances in Medicine and Medical Research, 33 (19). pp. 151-156. ISSN 2456-8899

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Official URL: https://doi.org/10.9734/jammr%2F2021%2Fv33i1931090

Abstract

Introduction: Hypertension complicates 10% of pregnancies causing significant morbidity and mortality worldwide. It is considered severe hypertension if Systolic >160 and Diastolic >110 lasting more than 15 minutes. It is an Obstetric emergency and needs prompt appropriate treatment.

Methods: A quasi-experimental study was conducted at Tehsil Headquarter Hospital. One hundred fifty patients were included in the study divided into two groups: Nifedipine group (n:75) getting oral Nifedipine and Labetalol group (n:75) getting IV Labetalol.

Results: This study shows that goal therapeutic blood pressure was reached earlier in patients receiving oral Nifedipine 28.2 ± 11.7minutes as compared with those receiving intravenous Labetalol 48.4 +- 23.5minutes.

Fewer doses were required for the nifedipine group in contrast to the IV labetalol group Failure of treatment was higher among the IV labetalol group.

Conclusion: Oral nifedipine is as productive and safe as compared to Iv labetalol and is more convenient in Low resource settings.

Item Type:	Article
Subjects:	Institute Archives > Medical Science
Depositing User:	Managing Editor
Date Deposited:	25 Feb 2023 06:31
Last Modified:	28 Sep 2023 08:13
URI:	http://eprint.subtopublish.com/id/eprint/154

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