AI delivers Michaelis constants as fuel for genome-scale metabolic models

Antolin, Albert A. and Cascante, Marta (2021) AI delivers Michaelis constants as fuel for genome-scale metabolic models. PLOS Biology, 19 (10). e3001415. ISSN 1545-7885

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Abstract

Michaelis constants (Km) are essential to predict the catalytic rate of enzymes, but are not widely available. A new study in PLOS Biology uses artificial intelligence (AI) to accurately predict Km on a proteome-wide scale, paving the way for dynamic, genome-wide modeling of metabolism.

Item Type: Article
Subjects: Institute Archives > Biological Science
Depositing User: Managing Editor
Date Deposited: 21 Jan 2023 04:39
Last Modified: 07 Mar 2024 03:55
URI: http://eprint.subtopublish.com/id/eprint/1256

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